Cancer Gene mutational signature for SUM-185

Exome sequencing based detection of mutations in the SUM-185 cell line that appear in the COSMIC data base. The genes in red were hits in

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Copy number data for candidate oncogenes in each cell line
Point mutation data for genes recurrently mutated in cancer
Genome-wide expression data
Genome-scale shRNA interference screen data for all cell lines with hit data displayed on KEGG pathways
Genome-scale CRISPR screen data for all cell lines with hit data displayed on KEGG pathways
Narrative summary describing how each SUM cell line was developed and descriptions of originating sources and characteristics of 40 other breast cancer cell lines
Drug sensitivity data from the Genomics of Drug Sensitivity in Cancer data base, linked to a data mining tool for each cell line in the database
A Bibliography of peer-reviewed papers containing data obtained with each SUM cell line