The Oncogene Signatures of the SUM-1315 cell line

Candidate Oncogene Signature: Genes that are genomically altered and OncoKB annotated
GeneSymbol DnaAmp LogFoldChange Mutation OccurencesInCOSMIC oncogene
TP53 NULL 0.0686 TP53p.C135F 46 0

Functional Oncogene Signature: Genes that are genomically altered and were hits in our RNAi screen

GeneSymbol DnaAmp LogFoldChange Mutation OccurencesInCOSMIC ScreenHit
RNF182 1.534 5.742 NULL NULL 1
Overall Oncogene Signature: Genes that are amplified and overexpressed or recurrently mutated regardless of OncoKB or RNAi status
GeneSymbol DnaAmp LogFoldChange Mutation ScreenHit OccurencesInCOSMIC ExistingDrugs
CD83 1.534 1.199   0    
RNF182 1.534 5.742   1    
SIRT5 1.534 1.240   0    
TP53   0.068 TP53p.C135F 0 46  
 

 

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