Below are the genes with point mutations in SUM-190 for any mutation with at least one occurrence in COSMIC
| gene | geneMutation | Occurences_in_COSMIC |
| AGXT | AGXTp.A186V | 2 |
| ANAPC1 | ANAPC1p.T416M | 1 |
| CACHD1 | CACHD1p.T657N | 1 |
| CD274 | CD274p.R260C | 1 |
| CDC27 | CDC27p.I487V | 1 |
| CELSR1 | CELSR1p.W1958G | 3 |
| DCHS2 | DCHS2p.P2851L | 1 |
| FAM194A | FAM194Ap.R374C | 1 |
| KIAA1274 | KIAA1274p.R646W | 1 |
| KIAA1522 | KIAA1522p.A689T | 1 |
| LAMA3 | LAMA3p.V206G | 1 |
| NBPF14 | NBPF14p.V897L | 1 |
| OR5B12 | OR5B12p.K301N | 1 |
| PIK3CA | PIK3CAp.H1047R | 1889 |
| RBMX | RBMXp.P167A | 1 |
| SCNN1B | SCNN1Bp.Q15E | 2 |
| SIRPB1 | SIRPB1p.T248A | 5 |
| SLC4A11 | SLC4A11p.V691G | 1 |
| TCN2 | TCN2p.T333M | 1 |
| WDR37 | WDR37p.D354A | 1 |
| ZAK | ZAKp.H651R | 1 |
| ZNF208 | ZNF208p.V325F | 1 |
Note the PIK3CA mutation, and this gene WAS a hit in the functional screen
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