SUM-229 Home

The SUM-229PE cell line was derived from a small pleural effusion specimen that came to the lab.  The resulting cell line is a classic triple negative breast cancer cell line of the basal subtype.  And, like many such cell lines, these cells have a KRAS point mutation, a common TP53 mutation and they overexpress MYC at the mRNA level.

Okay, let’s delve more deeply into the SUM-229 cell line.
  1. Derivation of the SUM-229 cell line
  2. Narrative Summary of the SUM-229 cell line
  3. Genomic alterations of the SUM-229 cell line
  4. The KEGG canonical pathways enriched with data from our genome-scale shRNA screen
  5. Functional-druggable signature for SUM-229 cells
  6. Bibliography of published papers in which SUM-229 cells were used
  7. SUM-229 Blog

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